Dopamine and its receptors are intimately involved in the pathogenesis of nearly every psychiatric disorder. While we clinicians use multiple treatments that affect these receptors, lack of deep knowledge of these receptors often leads to “blind” prescribing, resulting in suboptimal prescribing. To compound it further, many new psychotropics have vastly different and more precise effects on dopamine receptor family. There is urgent need for continuing medical education on the dopamine family of receptors and means by which we clinicians can target it precisely.