This session will examine the research literature on the diagnostic validity of the “major depressive disorder” concept, and the alternative diagnoses of “manic-depressive illness” and “neurotic depression.” The treatment of the types of depressive states, specifically melancholia, mixed depression, vascular, and neurotic depression, will be examined. The limitations of antidepressants in specific subtypes will be reviewed, as well as data on the benefits of neuroleptics (dopamine blockers) and mood stabilizers. This session will provide attendees with a means of applying that knowledge in clinical practice. Clinical applications will be emphasized.
