We strive for wellness through a healthy diet, exercise, and prioritizing time for adequate sleep. Recent evidence confirms the important role of sleep for optimum cognitive, metabolic, endocrine, and immune functioning. Emerging data now shows that the timing of our sleep-wake patterns, as well as what we eat and when we eat it, further influences our biological rhythms and impacts our health. This session will provide an update of recent scientific literature focused on sleep, diet, and biological rhythms, and then review translational approaches that highlight modifiable behaviors that can help us enhance our health.