Benzodiazepines are some of the America’s most widely used medications, and they undeniably have helped a large number of patients. However, recent data shows that they harm a previously unknown, large number of patients. Risks include physical dependence, addiction, withdrawal seizures, memory problems, dementia risk elevation, and falls. A new black box warning regarding co-administration of these drugs is now part of the U.S. Food and Drug Administration directive to us clinicians. Despite clear reasons for concern, these drugs are also necessary and effective in multiple acute and chronic settings. The goal of this session is to offer state-of-the-art information on the risk–benefit profile of these medications and offer clear, practical advice to clinicians in order to minimize harm and maximize benefits.
